Dados do Trabalho
Título
Association of Comorbid Insomnia and Obstructive Sleep Apnea (COMISA) with Depressive Symptoms in a Population Sample
Introdução
Insomnia Disorder (ID) and Obstructive Sleep Apnea (OSA) are two of the most common sleep disorders in the general population. Recently, the co-occurrence of these two conditions, known as COMISA, has garnered attention due to its potential impact on psychiatric disorders like anxiety and depression.
Objetivo
The aim of this study is to evaluate whether the association of these disorders (COMISA) leads to an additive effect of morbidity on psychiatric symptoms in a population-based sample from São Paulo.
Métodos
Cross-sectionally, 769 participants from the EPISONO 2018 study were evaluated. Four groups were identified: COMISA Group (IAH > 15 and ISI > 15), Insomnia Disorder (ID) Group (ISI > 15), OSA Group (IAH > 15), and Non-ID Non-OSA Group (no sleep apnea or insomnia). A linear regression analysis was conducted with the Beck's Depression Inventory (BDI) score as the dependent variable. The data were analyzed using the Jamovi program, employing a Generalized Linear Model (GzLM) with a significance level set at p < 0.05. To account for potential confounding factors, adjustments were made for age, sex, and BMI.
Resultados
Among the 769 participants, 36 had COMISA, 102 had only ID, 119 had OSA, and 490 had neither ID nor OSA. Regression analysis revealed that only ID was significantly associated with a higher BDI score, with an average increase of 6.76 points (p < 0.001; CI 5.10-8.43), after adjusting for age, BMI, and sex. OSA and COMISA did not reach statistical significance (p > 0.05).
Conclusões
The study found that ID is significantly associated with higher levels of depression scores. In contrast, OSA and COMISA did not significantly affect this measure in the general population. The study's non-clinical sample, relatively small sample size, and cross-sectional design are potential limitations.
Palavras -chave
Insomnia
Obstructive Sleep Apnea
Comorbid Insomnia and Obstructive Sleep Apnoea (COMISA)
Psychiatric Symptoms
Beck's Depression Inventory
Depression
Population Sample
Área
Área Clínica
Instituições
UNIFESP - São Paulo - Brasil
Autores
CARLOS RENATO PERIOTTO, DALVA ROLLEMBERG POYARES, Monica Levy Andersen, Sergio Tufik, Gabriel Natan Pires