Dados do Trabalho

Título

Impact of overlapping Obstructive Sleep Apnea Syndrome on functional performance of patients with Chronic Obstructive Pulmonary Disease

Introdução

Functional performance is an important prognostic marker in chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea syndrome (OSAS). However, the impact of the overlap of these diseases has been little studied.

Objetivo

To assess whether the presence of OSAS can negatively impact functional performance in patients with COPD during submaximal exercise.

Métodos

Thirty patients underwent pulmonary function tests, echocardiograms and home sleep tests to confirm the diagnosis, stage the disease, exclude any cardiac abnormalities and allocate them to groups (COPD n=15; COPD+OSA n=15). They then performed the six-minute walk test (6MWT) to assess functional capacity, measured in meters walked.

Resultados

There was a predominance of females in the COPD group (n=9) and males in the COPD+OSAS group (n=12). In addition, older age was observed for the COPD+OSAS group compared to the COPD group (69 years vs. 63 years, respectively), and worse functional performance (330±24 meters), also for the COPD+OSAS group vs. (420±16 meters) walked by the COPD group. Furthermore, it was possible to observe a negative and moderate association (r= -0.48; p= 0.008) between AHI and PD.

Conclusões

OSAS, when coexisting with COPD, negatively impacts functional capacity. AHI is associated with functional impairment in these patients.

Palavras -chave

COPD; OSAS; functional capacity; 6MWT; overlap syndrome.